Clone High is an American adult animated science fiction sitcom created by Phil Lord, Christopher Miller and Bill Lawrence that premiered on Canadian cable channel Teletoon's late-night programming block The Detour On Teletoon on November 2, 2002. Set at a high school populated by the clones of well-known historical figures, the series follows its central cast which includes adolescent depictions of Abe Lincoln, Joan of Arc, Gandhi, Cleopatra, and JFK. The series also serves as a parody of teen dramas such as Dawson's Creek and Beverly Hills, 90210; every episode is introduced as a "very special episode".Lord and Miller first developed the series' concept, originally titled Clone High School, USA!, while at Dartmouth College in the 1990s, later pitching it to executives at US network Fox Broadcasting Company, who ultimately decided to pass on the program. It was later purchased by cable channel MTV, and was produced between 2002 and 2003. The show's design is heavily stylized and its animation style limited, emphasizing humor and story over visuals. The Clone High theme song was written by Tommy Walter and performed by his alternative rock band Abandoned Pools, who also provided much of the series' background music.

It was first aired in its entirety on Teletoon in Canada between 2002 and 2003, later premiering on MTV in the US on January 20, 2003. It became embroiled in controversy regarding its depiction of Gandhi soon afterward, which prompted over 100 people in India to mount a hunger strike in response. Shortly after, MTV cancelled the series, which had been receiving low ratings; the last episodes of season 1 were seen in 2016 on MTV Classic in the United States. Clone High attracted mixed reviews from television critics upon its premiere, but it has since received critical acclaim and a cult following.

On July 2, 2020, it was announced that a revival of the series was in the works at MTV Entertainment Studios with the original creators Lord, Miller, and Lawrence returning. On February 10, 2021, it was announced that HBO Max (later Max) had ordered two seasons of the revival, which premiered on May 23, 2023. On April 5, 2023, a teaser for the revival was uploaded on Max's official YouTube channel. The final trailer was released on May 8. The revival premiered on Tuesday May 23, 2023, with season 2 releasing two new episodes and then moving to Thursday with its second batch of episodes the next week and continued until June 22. The second season of the revival (third season overall) premiered with all 10 episodes on February 1, 2024.