Gary & Mike is an American adult animated buddy comedy sitcom that aired on UPN in 2001 and Comedy Central in 2003. It was Big Ticket Television’s first animated show. The show was produced in stop motion clay animation and lasted only one season. A total of thirteen episodes were produced. The series was initially proposed to Fox, but was eventually passed over to UPN. UPN had aired the episodes out of order, leading to inconsistencies within the plot serialization (save for the production placement of the third and fourth episodes).

In addition to its own musical score by Greg O'Connor and title theme by Bottlefly, the series has had a number of licensed songs that can be heard throughout most of the episodes.The Sizzle that was initially proposed to Fox was animated by Corky Quakenbush before the series was passed over to Will Vinton Studios. It featured the songs Girls by Beastie Boys and Heroes by The Wallflowers.