Lucky Louie is an American television sitcom created by Louis C.K., which aired on HBO in the U.S. for one season in 2006 — and in Canada on Movie Central, The Movie Network, and The Comedy Network. As the show's creator, writer and executive producer, C.K. also starred as the eponymous central character, a part-time mechanic at a muffler shop.

A first for HBO, Lucky Louie was filmed before a live studio audience, in a multiple-camera setup. Inspired by Norman Lear's sitcoms, the show depicts the life of an average working class family while using spartan sets and wardrobe. Dealing with a range of topics including sex and racism, the series uses considerable adult language and featured guest stars best known as stand-up comedians, including Jim Norton, Laura Kightlinger, Nick DiPaolo, Todd Barry and Rick Shapiro.

HBO ordered 12 episodes, which aired during the 2006 summer season, as well as eight scripts for a second season, before canceling the show in September 2006 — for numerous reasons ranging from the nature of the show to network economic pressure.