Diff'rent Strokes is an American television sitcom, which aired on NBC from November 3, 1978, to May 4, 1985, and on ABC from September 27, 1985, to March 7, 1986. The series stars Gary Coleman and Todd Bridges as Arnold and Willis Jackson, respectively, who are two boys from Harlem taken in by a wealthy Park Avenue businessman and his daughter. Phillip Drummond (Conrad Bain) is a widower for whom their deceased mother previously worked; his daughter, Kimberly, is played by Dana Plato. During the first season and the first half of the second season, Charlotte Rae also starred, as Mrs. Edna Garrett, the Drummonds' first housekeeper, who ultimately spun off into her own sitcom, The Facts of Life, as a housemother at the fictional Eastland School. The second housekeeper, Adelaide Brubaker, was played by Nedra Volz. The third housekeeper, Pearl Gallagher, was played by Mary Jo Catlett, first appearing as a recurring character, later becoming a main cast member.

The series made stars of Coleman, Bridges, and Plato and became known for the "very special episodes", in which serious issues such as racism, illegal drug use, alcoholism, hitchhiking, kidnapping, and child sexual abuse were dramatically explored.