House of Wax is a 1953 American period mystery-horror film directed by Andre de Toth. A remake by Warner Bros. of their 1933 film Mystery of the Wax Museum, it stars Vincent Price as a disfigured sculptor who repopulates his destroyed wax museum by murdering people and using their wax-coated remains as displays. The film premiered in New York on April 10, 1953, and had a general release on April 25, making it the first 3D film with stereophonic sound to be presented in a regular theater and the first color 3D feature film from a major American studio (Columbia Pictures' Man in the Dark, the first major-studio black-and-white 3D feature, premiered two days before House of Wax).

In 1971, the film was re-released to theaters in 3D with a full advertising campaign. Newly struck prints of the film in Chris Condon's single-strip StereoVision 3D format were used for this release. Another major re-release occurred during the 3D boom of the early 1980s. Warner Bros. released a loose remake of the film in 2005.

The Library of Congress selected House of Wax for preservation in the National Film Registry in 2014, deeming it "culturally, historically, or aesthetically significant".