The Medicine Bottle is a 1909 American silent thriller film written and directed by D. W. Griffith, produced by the American Mutoscope and Biograph Company in New York City, and starring Florence Lawrence, Adele DeGarde, and Marion Leonard. At its release in March 1909, the short was distributed to theaters on a "split reel", which was a single projection reel that accommodated more than one film. This drama shared its reel with another Biograph short directed by Griffith, the comedy Jones and His New Neighbors.Original contact-print paper rolls of both motion pictures, as well as projectable safety-stock copies of them, are preserved in the Library of Congress.