The Dirty Dozen: The Deadly Mission is a 1987 made-for-TV film and is the second sequel to the original The Dirty Dozen. It features an all-new 'dirty dozen,' this time under the leadership of Major Wright (Telly Savalas, playing a different role than in the 1967 film).

Learning of a Nazi plot to attack Washington, D.C., with a deadly nerve gas, Major Wright leads twelve convicts on a suicide mission deep into occupied France to destroy the secret factory where the poison is made.