The Devil at 4 O'Clock is a 1961 American adventure film directed by Mervyn LeRoy and starring Spencer Tracy and Frank Sinatra. Based on a 1958 novel with the same title by British writer Max Catto, the film was a precursor to Krakatoa, East of Java and the disaster films of the 1970s such as The Poseidon Adventure, Earthquake and The Towering Inferno.

The film deals with multiple issues of prejudice concerning age, blindness, disease and alcoholism. It also considers moral issues, such as a priest who drinks to excess and criminals who commit acts of self-sacrifice.