Despicable Me 3 is a 2017 American animated comedy film produced by Illumination and distributed by Universal Pictures. It is the sequel to Despicable Me 2 (2013), and the third main and fourth overall installment in the Despicable Me franchise. The film was directed by Pierre Coffin and Kyle Balda, co-directed by production and character designer Eric Guillon, and produced by Chris Meledandri and Janet Healy, from a screenplay written by the writing team of Cinco Paul and Ken Daurio. It stars the voices of Steve Carell, Kristen Wiig, Trey Parker, Coffin, Miranda Cosgrove, Steve Coogan, Jenny Slate, Dana Gaier, Nev Scharrel, and Julie Andrews. In the film, Gru teams up with his long-lost twin brother Dru to stop Balthazar Bratt, a former child actor of the 1980s, from destroying Hollywood after his show is canceled.

Despicable Me 3 debuted at the Annecy International Animated Film Festival on June 14, 2017, and was theatrically released in the United States on June 30. Despite receiving mixed reviews from critics, the film grossed $1.035 billion worldwide, becoming the fourth-highest-grossing film of 2017 and the fourth-highest-grossing animated film of all time during its theatrical run. A sequel, Despicable Me 4, is scheduled for release in July 3, 2024.