Mountains of the Moon is a 1990 American biographical film depicting the 1857–1858 journey of Richard Francis Burton and John Hanning Speke in their expedition to Central Africa, which culminated in Speke's discovery of the source of the Nile River and led to a bitter rivalry between the two men. The film stars Patrick Bergin as Burton and Iain Glen as Speke. Delroy Lindo appears as an African whom the explorers meet.

The film was directed by Bob Rafelson based on the 1982 novel Burton and Speke by William Harrison.