Killer Joe is a 2011 American Southern Gothic crime film directed by William Friedkin. The screenplay by Tracy Letts is based on his 1993 play of the same name. The film stars Matthew McConaughey in the title role, Emile Hirsch, Juno Temple, Gina Gershon, and Thomas Haden Church.

In the film, the estranged family of a woman scheme to kill her in order to collect on her life insurance policy. They realize too late that they are not the actual beneficiaries of the policy, and the co-conspirators quickly turn against each other.