NXT TakeOver: Stand & Deliver was the 34th NXT TakeOver and inaugural Stand & Deliver professional wrestling pay-per-view (PPV) and livestreaming event produced by WWE. It was held for wrestlers from the promotion's NXT brand division. The event took place during WrestleMania 37 week on April 7 and 8, 2021, and was broadcast from the Capitol Wrestling Center, hosted at the WWE Performance Center in Orlando, Florida. It was the only TakeOver to take place over the span of two nights. Both nights aired on the WWE Network internationally, and was also the first WWE in-ring event to air on Peacock in the United States, following the shutdown of the aforementioned service's standalone American version on April 4. The first night also aired on the USA Network in NXT's weekly Wednesday night timeslot, making it the only TakeOver to air on television as well as the final NXT broadcast on Wednesdays before moving to Tuesdays on April 13, while the second night aired on traditional PPV in addition to the livestreaming services.

The card consisted of 12 matches evenly divided across both nights, including one match on the pre-show for each night. In the main event for Night 1, Raquel González defeated Io Shirai to win the NXT Women's Championship. Other prominent matches included Walter defeating Tommaso Ciampa to retain the NXT United Kingdom Championship and MSK (Wes Lee and Nash Carter) defeated Grizzled Young Veterans (James Drake and Zack Gibson) and Legado Del Fantasma (Raul Mendoza and Joaquin Wilde) to win the vacant NXT Tag Team Championship. Two matches were promoted as main event matches for Night 2. In what was the final match on the card, Kyle O'Reilly defeated Adam Cole in an unsanctioned match. In the penultimate match that was promoted as the other main event match, Karrion Kross defeated Finn Bálor to win the NXT Championship. In another prominent match on the undercard which opened the event, Santos Escobar defeated Jordan Devlin in a ladder match to determine the undisputed NXT Cruiserweight Champion.

While the NXT TakeOver series was discontinued in September, the Stand & Deliver event continued on, with a second event scheduled for the following year to be held during WrestleMania 38 weekend. This in turn established Stand & Deliver as NXT's annual event held during WrestleMania week. This was also the only Stand & Deliver event to air on PPV, as beginning with the following year's event, NXT's major events are only available via WWE's livestreaming platforms.