The Substitute 2: School's Out is a 1998 straight-to-DVD action-crime-thriller film directed by Steven Pearl and starring Treat Williams as Carl Thomasson (later spelled Karl in the sequels), a mercenary who masquerades as a teacher in order to enter a tough urban school and wreak his revenge upon his brother's killer.

The film has very little connection to The Substitute, other than Joey Six (protagonist Jonathan Shale's only surviving mercenary in the first film, this time portrayed by Angel David instead of Raymond Cruz) aiding Thomasson during the course of the movie. A reference early in the film indicates, through a photograph and short conversation between Thomasson and Joey Six, that Shale and Jane Hetzko (Shale's girlfriend) had married and now teach in foreign nations as part of the Peace Corps. It is also noted that Shale and Thomasson had served in the Army, as well as worked as mercenaries together.