Curious George 2: Follow That Monkey! is a 2009 American animated comedy film based on the children's stories by H.A. Rey and Margret Rey. It is a sequel to the 2006 film Curious George. It was originally titled Curious George 2: Monkey on the Run. It was released straight to DVD in the United States and theatrically in Denmark, Sweden, and Iceland.

While Frank Welker and Ed O'Ross reprise their roles from the first film as George and Ivan respectively, several other roles were recast. Will Ferrell, the voice of Ted (The Man with the Yellow Hat), was replaced by Jeff Bennett, reprising his role from the television series; Drew Barrymore, the voice of Maggie, was replaced by Nickie Bryar; Dick Van Dyke, the voice of Mr. Bloomsberry, was replaced by Fred Tatasciore. Clint Howard voices Balloon Man in the first film, but in the sequel, voices Farmer Dan. Tim Curry, Jamie Kennedy, Matt Lauer, and Jerry Lewis voice the new characters. Ron Howard, who is the producer of the 2006 film, returns as executive producer, along with his partner Brian Grazer.