Fullmetal Alchemist: Brotherhood (Japanese: 鋼の錬金術師 FULLMETAL ALCHEMIST, Hepburn: Hagane no Renkinjutsushi) is a Japanese anime television series adapted from the original Fullmetal Alchemist manga series by Hiromu Arakawa. Produced by Bones, the series is directed by Yasuhiro Irie, written by Hiroshi Ōnogi and composed by Akira Senju. The series was conceived in order to create a faithful adaptation that directly follows the entire storyline of the original manga, after 2003's Fullmetal Alchemist anime series strayed away from it to tell its own story after running out of published manga material to adapt.

Production for Fullmetal Alchemist: Brotherhood began in 2008. The series was broadcast for sixty-four episodes on MBS–TBS from April 2009 to July 2010. The series was first licensed in North America by Funimation and was broadcast English-dubbed on Adult Swim from February 2010 to September 2011. In 2016, Funimation lost the rights to the series and it was transferred to Aniplex of America.

Fullmetal Alchemist: Brotherhood earned acclaim from critics and audiences, and is considered to be one of the best anime series of all time. Reviewers noted its faithfulness to the manga and its introduction of characters and plot details that were not present in the 2003 anime; the climactic episodes were also lauded for both its action scenes and moral messages.