The United States vs. Billie Holiday is a 2021 American biographical drama film about singer Billie Holiday, based on the book Chasing the Scream: The First and Last Days of the War on Drugs by Johann Hari. Directed by Lee Daniels, the film stars Andra Day in the title role, along with Trevante Rhodes, Garrett Hedlund, Leslie Jordan (in his final film appearance), Miss Lawrence, Adriane Lenox, Natasha Lyonne, Rob Morgan, Da'Vine Joy Randolph, Evan Ross, and Tyler James Williams.

Initially set to be released theatrically in the United States by Paramount Pictures, the film was sold to Hulu in December 2020 and digitally released in the United States on February 26, 2021. The United States vs. Billie Holiday received mixed reviews from critics; while Day's performance was praised, the direction and screenplay were criticized as unfocused. For her performance, Day was nominated for the Academy Award for Best Actress and won the Golden Globe Award for Best Actress – Motion Picture Drama. The film was also nominated for the Golden Globe Award for Best Original Song ("Tigress and Tweed") and the soundtrack won the Grammy Award for Best Compilation Soundtrack for Visual Media, for Andra Day, Salaam Remi, and Lynn Fainchtein.